Population pharmacokinetics of theophylline during paediatric extracorporeal membrane oxygenation
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چکیده
منابع مشابه
Pharmacokinetics of anidulafungin during venovenous extracorporeal membrane oxygenation
Echinocandins are currently considered the first-line treatment for invasive candidiasis (IC) in the intensive care unit (ICU) [1, 2]. However, extracorporeal membrane oxygenation (ECMO), a rescue therapy used in patients with severe acute respiratory distress syndrome (ARDS) [3], could alter the pharmacokinetics of certain drugs [4]. We prescribed anidulafungin for suspected IC in a patient wi...
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Sir, Extracorporeal membrane oxygenation (ECMO) is a supportive therapy and definitive management often relies on adequate drug therapy aimed at reversing the underlying cause of cardiac and/or respiratory failure. Despite this, a paucity of data exists describing the impact of ECMO on pharmacokinetics (PK) and antibiotic dosing requirements. By default, clinicians prescribe standard doses to t...
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INTRODUCTION The aim of this study was to describe the population pharmacokinetics of vancomycin in critically ill patients treated with and without extracorporeal membrane oxygenation (ECMO). METHODS We retrospectively reviewed data from critically ill patients treated with ECMO and matched controls who received a continuous infusion of vancomycin (35 mg/kg loading dose over 4 hours followed...
متن کاملResource use and health outcomes of paediatric extracorporeal membrane oxygenation.
The use of extracorporeal membrane oxygenation can be rationalised by the assumption that non-zero survival after refractory cardiorespiratory failure represents improved outcome. Survivors may have cognitive and or functional morbidities, require complex ongoing care, and as a consequence consume considerable healthcare resources.
متن کاملLack of effect of extracorporeal membrane oxygenation on tigecycline pharmacokinetics.
Prevalence of faecal carriage of Enterobacteriaceae with NDM-1 carbapenemase at military hospitals in Pakistan, and evaluation of two chromogenic media. Sir, Extremely limited data are available on the pharmacokinetics of antimicrobial agents during extracorporeal membrane oxygen-ation (ECMO). We report the case of a young adult patient who was admitted on day 1 to our intensive care unit for a...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 2003
ISSN: 0306-5251
DOI: 10.1046/j.1365-2125.2003.01735.x